Home » Lab-grown muscle robots now jump, walk, swim and grab

Lab-grown muscle robots now jump, walk, swim and grab

by Lisa Larsen
A tiny translucent gel robot with a red strip of muscle jumping above a petri dish.

A robot the size of a fingernail has just jumped, swum, walked and grabbed things, powered by real muscle grown in a lab. Engineers at ETH Zurich designed the living muscle and its soft “skeleton” together on a computer, and their tiny machines now move up to 11 times more than earlier ones with the same amount of muscle, they report in Nature Communications.

Why it matters: muscle is a wonderful motor. It is soft, quiet, efficient and can even repair itself, things metal motors can’t do. “Biohybrid” robots (part machine, part living tissue) could one day work in fragile places, such as inside the body or in delicate environments. Their big problem so far: they barely moved. This study tackles exactly that.

Design the muscle and the body together

Each little actuator (the part that makes the movement) is about 1.5 cm long. It combines skeletal muscle grown from mouse muscle cells with a soft, water-rich gel called a hydrogel, which acts as the skeleton. Until now, teams usually grew the muscle first and then built a body around it.

The ETH Soft Robotics Lab, led by Professor Robert Katzschmann, flipped that. A computer simulation decided where muscle should go, how much of it, and how stiff the gel should be, then searched for the layout that made the whole part move the most. “Instead of specifying a fixed form for our muscle geometry, we wanted to design the whole thing from scratch on the computer,” says co-lead author Aiste Balciunaite. IEEE Spectrum describes the same co-design approach, built on an adapted soft-body simulator.

A clear gel block with fine grooves holding neatly aligned pink muscle fibres.
Grooves in the gel line up the muscle fibres · Illustration by DIGITAL WOXTER TECHNEWS.

The gel skeletons are printed with light in about a minute each, using a method called xolography that hardens a whole shape inside a vat of liquid. Fine grooves in the gel anchor the muscle and line up its fibres, like combing hair in one direction, so less force is lost.

Jump, walk, swim, grab

The results are easy to see, literally. “With previous systems, you sometimes had to look under a microscope to see the flexing,” Balciunaite says. Now a single contraction lifts the actuator about 5 mm, roughly a third of its own length. A walking version moves at 6.2 mm per second, which ETH says is faster for its body size than any walking biohybrid robot reported so far. Other versions swim, crawl across a surface and grasp objects, confirms IEEE Spectrum.

The catch: living muscle needs feeding

These robots are not leaving the lab any time soon. The muscle has to sit in a nutrient solution to stay alive, so long-term use is still far off, ETH notes. Living tissue also varies, so no two actuators behave exactly alike, unlike factory-made parts. And anything bigger would need its own artificial blood supply to bring in oxygen and food and take away waste, which Katzschmann calls one of the biggest challenges.

A humanoid robot with red muscle fibres standing in a bright living room.
Muscle-powered robots at home are still a long way off · Illustration by DIGITAL WOXTER TECHNEWS.

What happens next

The team now wants to understand and control how muscle matures in the lab, and to work on that artificial vascular system. “We’re just beginning to build robots in a more natural way,” Katzschmann says. It’s a fun contrast with robots that copy nature with springs and motors, like the frog-like robot with snapping legs: here the robot uses nature’s own motor.

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